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HIGHLIGHTS

Burns L, Giannakopoulou N, Zhu L, Xu YZ, Khan RH, Bekal S, Schurr E, Schmeing TM, Gruenheid S. The bacterial virulence factor NleA undergoes host-mediated O-linked glycosylation. Mol Microbiol 2022.

Cannon T, Sinha A, Trudeau LE, Maurice CF, Gruenheid S. Characterization of the intestinal microbiota during Citrobacter rodentium infection in a mouse model of infection-triggered Parkinson's disease. Gut Microbes 2020.

Matheoud D*, Cannon T*, Voisin A, Penttinen AM, Ramet L, Fahmy AM, Ducrot C, Laplante A, Bourque MJ, Zhu L, Cayrol R, Le Campion A, McBride HM*, Gruenheid S*, Trudeau LE*, Desjardins M*. Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice. Nature 2019.

Kang E, Zhou G, Yousefi M, Cayrol R, Xia J, Gruenheid SLoss of disease tolerance during Citrobacter rodentium infection is associated with impaired epithelial differentiation and hyperactivation of T cell responses. Sci Rep 2018.

Graphical abstract of "Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice" Nature paper.

 

Thomassin JL, Leclerc JM, Giannakopoulou N, Zhu L, Salmon K, Portt A, Daigle F, Le Moual H, Gruenheid SSystematic Analysis of Two-Component Systems in Citrobacter rodentium Reveals Positive and Negative Roles in Virulence. Infect Immun 2017.

Kang E, Yousefi M, Gruenheid SR-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice. PLoS One 2016.

Thomassin JL, Giannakopoulou N, Zhu L, Gross J, Salmon K, Leclerc JM, Daigle F, Le Moual H, Gruenheid SThe CpxRA two-component system is essential for Citrobacter rodentium virulence. Infect Immun 2015.

Papapietro O, Teatero S, Thanabalasuriar A, Yuki KE, Diez E, Zhu L, Kang E, Dhillon S, Muise AM, Durocher Y, Marcinkiewicz MM, Malo D, Gruenheid SR-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea. Nat Commun 2013.

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